منابع مشابه
Droplet-Generating Microfluidic Devices for Soluble Assays
ogy in the pharmaceutical industry (1). Over the past decade, there has been a logarithmic increase in the industry’s ability to screen large combinatorial libraries of compounds against target molecules (2). The technology to achieve this has come in the form of robotics, high-density microplates, small volume (microliter) liquid handling, and sophisticated detection schemes. Signifi cant effo...
متن کاملIntegrated microfluidic devices for combinatorial cell-based assays.
The development of miniaturized cell culture platforms for performing parallel cultures and combinatorial assays is important in cell biology from the single-cell level to the system level. In this paper we developed an integrated microfluidic cell-culture platform, Cell-microChip (Cell-microChip), for parallel analyses of the effects of microenvironmental cues (i.e., culture scaffolds) on diff...
متن کاملMicrofluidic Devices for Drug Delivery Systems and Drug Screening
Microfluidic devices present unique advantages for the development of efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Compared to bulk methods, by efficiently controlling the geometries of the fabricated chip and the flow rates of multiphase fluids, microfluidic technology enables the generation of highly stable, uniform, mo...
متن کاملMicrofluidic devices for bioapplications.
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful tool that is currently revolutionizing chemical and biological analysis by replicating laboratory bench-top technology on a miniature chip-scale device, thus allowing assays to be carried out at a fraction of the time an...
متن کاملExpanding the available assays: adapting and validating In-Cell Westerns in microfluidic devices for cell-based assays.
Microfluidic methods for cellular studies can significantly reduce costs due to reduced reagent and biological specimen requirements compared with many traditional culture techniques. However, current types of readouts are limited and this lack of suitable readouts for microfluidic cultures has significantly hindered the application of microfluidics for cell-based assays. The In-Cell Western (I...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: High-Throughput
سال: 2018
ISSN: 2571-5135
DOI: 10.3390/ht7020018